Antonio Banderas

Chris Evans/Big Boy

Terry Crews/Nancy O'Dell

Courteney Cox & Craig Ferguson/Jessica Radloff

Tobey Maguire

David Oyelowo/OMI

James Brolin & Dianne Wiest

James Brolin and Dianne Wiest (Life in Pieces (2015)); entertainment reporter Kevin Frazier (Entertainment Tonight (1981)).

Kunal Nayyar/Chi-Lan Lieu

Kunal Nayyar (The Big Bang Theory (2007)); lifestyle expert Chi-Lan Lieu unveils the hottest must-haves for fall.

Lea Michele/Leona Lewis

Actress/author Lea Michele (Scream Queens (2015) and (book "You First: Journal Your Way to Your Best Life")). Also: Leona Lewis performs.

Pauley Perrette & Sean Murray

Pauley Perrette and Sean Murray (NCIS (2003)); entertainment reporter Debbie Matenopoulos (Omg! Insider (2004)); Steve Moses, winner of Big Brother (2000). Also: chef Danny Boome serves up game-day dishes.

Marg Helgenberger

Marg Helgenberger on the series finale of CSI: Crime Scene Investigation (2000); entertainment reporter Debbie Matenopoulos (Omg! Insider (2004)).

Guest Co-Hostess Reba McEntire/Chris O'Donnell

Guest co-hostess Reba McEntire; Chris O'Donnell (NCIS: Los Angeles (2009)); radio personality Shelley Wade.

Guest Co-Hostess Alyssa Milano; Marcia Gay Harden, Luis Guzmán, Raza Jaffrey and Bonnie Somerville

Guest co-hostess Alyssa Milano; Code Black (2015) cast members Marcia Gay Harden, Luis Guzmán, Raza Jaffrey and Bonnie Somerville; entertainment reporter Kevin Frazier (Entertainment Tonight (1981)).

Shemar Moore

Shemar Moore (Criminal Minds (2005)); radio personality Jennifer Hutt.

Carol Burnett/GloZell Green

Carol Burnett; comedian GloZell Green; chef Richard Blais serves up game-day dishes.

Patricia Arquette

Patricia Arquette (CSI: Cyber (2015)).

John Stamos

John Stamos (Grandfathered (2015)); correspondent Jaymes Vaughan ("Ok TV" (2013)).

Ellen Page

Ellen Page (Freeheld (2015)); entertainment reporter Louis Aguirre (Omg! Insider (2004)).

Nina Dobrev

Nina Dobrev (The Vampire Diaries (2009)); YouTube personality Tyler Oakley. Also: lifestyle expert Chi-Lan Lieu unveils five products to take your look from day to night.

Tom Selleck

Tom Selleck (Blue Bloods (2010)); entertainment reporter Jessica Radloff. Also: chef Duff Goldman serves up game-day dishes.

Tim Daly/Sharon Osbourne's Birthday

Tim Daly (Madam Secretary (2014)). Also: Sharon Osbourne's birthday.

Shay Mitchell/Rachel Bloom

Author Shay Mitchell (Pretty Little Liars (2010) and (book "Bliss")); Lindsay Miller (Popsugar Now (2014)); Rachel Bloom (Crazy Ex-Girlfriend (2015)).

Kathy Bates

Kathy Bates (American Horror Story (2011)); entertainment reporter Nischelle Turner (Entertainment Tonight (1981)).

Kirsten Dunst

Kirsten Dunst (Fargo (2014)); radio personality Yesi Ortiz; entertainment reporter Nischelle Turner (Entertainment Tonight (1981)).

Jeff Daniels & Aaron Sorkin

Jeff Daniels and screenwriter Aaron Sorkin (Steve Jobs (2015)); entertainment reporter Keltie Knight (Omg! Insider (2004)). Also: restaurateur Craig Susser and chef Kursten Kizer make game-day dishes.

Colin Hanks/Linda Perry

Colin Hanks (Life in Pieces (2015)); radio personality Ellen K; singer-songwriter Linda Perry discusses her new children's album and performs.

Michael Weatherly & Eric Christian Olsen/Big Boy

Michael Weatherly (NCIS (2003)) and Eric Christian Olsen (NCIS: Los Angeles (2009)); radio personality Big Boy.

Gabrielle Union

Gabrielle Union (Being Mary Jane (2013)); entertainment reporter Michael Yo (Omg! Insider (2004)).

Jack Black

Jack Black (Goosebumps (2015)).

Meghan Trainor/Piers Morgan

Meghan Trainor; Piers Morgan. Also: chef David Guas prepares Asian grilled tri-tip tacos and fish kabobs.

Danielle Panabaker

Danielle Panabaker (The Flash (2014)); lifestyle expert Chi-Lan Lieu unveils five products to makeover a look in minutes.

Cast of Scorpion

Elyes Gabel, Robert Patrick, Ari Stidham and Eddie Kaye Thomas (Scorpion (2014)); entertainment reporter Jaymes Vaughan (Ok! TV (2013)).

Dick Van Dyke/Elle King

Author Dick Van Dyke (book, "Keep Moving"); Nancy O'Dell (Entertainment Tonight (1981)). Also: singer/songwriter Elle King performs and is interviewed.

Kate Bosworth/Cheryl Lynn; Sheryl Underwood's birthday celebration

Kate Bosworth (The Art of More (2015)); radio personality Ellen K; Sheryl Underwood's birthday celebration; R&B singer Cheryl Lynn performs.

Dr. Phil McGraw

Dr. Phil McGraw (Dr. Phil (2002)). Also: chef John Seymour makes buffalo chicken burgers with blue cheese.

2015 Halloween Celebration

A Halloween celebration features the hosts transforming into iconic musicians. Joey Fatone is a guest co-host.

Cast of Supergirl; Jason Derulo

Melissa Benoist , Calista Flockhart and Mehcad Brooks (Supergirl (2015)); singer/songwriter Jason Derulo performs.

Stephen Moyer

Entertainment Reporter Jessica Radloff

Shad Moss; Pati Jinich

Mary Steenburgen; Bridget Moynahan; Wendy Howard Goldberg

LL Cool J

In the studio is LL Cool J and radio personality Jenny Hutt.

Maura Tierney

Maura Tierney; Kevin Frazier. Also: Lifestyle expert Chi-Lan Lieu unveils "Shop Daytime Deals" for Thanksgiving entertaining.

Ian Somerhalder

Ian Somerhalder; designer Laurie Feltheimer. Also Chef Enzo Febbraro makes spaghetti carbonara frittata.

Daniel Radcliffe; Alanis Morissette

Daniel Radcliffe; Alanis Morissette

Diane Keaton

Diane Keaton; Entertainment Reporter Jaymes Vaughan.

Tracee Ellis Ross; Seal

Tracee Ellis Ross; Entertainment Reporter Kevin Frazier. Also: Seal performs.

Ian McKellen/Yesi Ortiz/Chi-Lan Lieu

Sam Clafin

Actor Sam Clafin; Nancy O'Dell. Also Chef Susan Feniger makes rib eye stuffed with garlic, and serrano chiles topped with chimichurri avacado goat cheese dip.

Olivia Wilde; Jake Lacy.

Olivia Wilde; Jake Lacy.

Poppy Montgomery/Rachael Ray/Ellen K

Guest co-hostess Poppy Montgomery; Ellen K. Also: Rachael Ray prepares Thanksgiving Day dishes.

Maura Tierney/Louis Aguirre/Lidia Bastianich

Maura Tierney (The Affair (2014)); entertainment reporter Louis Aguirre (Omg! Insider (2004)); chef Lidia Bastianich prepares roast chicken with orange and rosemary.

Episode 53

Krysten Ritter (Jessica Jones (2015)); chef Curtis Stone prepares a Thanksgiving Day feast.

Jenna Dewan Tatum;Bryshere

Jenna Dewan Tatum (SuperGirl); Bryshere "Yazz" Gray (Empire)

Mindy Kaling

Mindy Kaling

Morris Chestnut

Morris Chestnut; Entertainment editor Lindsay Miller.

Dolly Parton

Dolly Parton; Entertainment reporter Debbie Matenopoulos; ChefJason Santos makes apple-brined pork chops with Brussels sprouts skewers.

Toni Collette

Toni Collette; Lifestyle expert Chi-Lan Lieu unveils holiday gifts for neighbors and friends.

Wayne Brady

In NYC! Wayne Brady; Hollywood blogger Perez Hilton. Also: Julie Chen presents her annual "Top Chen List" of holiday gift items.

Jake McDorman

Actor Jake McDorman (Limitless); Radio personality Elvis Duran; Trisha Yearwood serves up a festive holiday dinner party meal and dessert.

"Downton Abbey" cast members

"Downton Abbey" cast members Hugh Bonneville, Michelle Dockery and Elizabeth McGovern; Radio personality Robin Quivers.

Jeffrey Dean Morgan

Jeffrey Dean Morgan; Radio personality Jenny Hutt. Also: Patty Smyth performs; Aisha Tyler and Sheryl Underwood take a football challenge from Phil Simms.

Josh Groban

Josh Groban; Columnist Michael Starr. Also: Holiday gifts for kids.

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Bridgit Mendler/Romany Malco

Guest Co-Hostess Poppy Montgomery, Debbie Matenopoulos, Zendaya

Guest Co-Hostess Poppy Montgomery, entertainment reporter Debbie Matenopoulos, Zendaya

Malin Akerman/Kevin Frazier

Malin Akerman of Billions and Kevin Frazier of Entertainment Tonight.

William Shatner, Debbie Matenopoulos, Chi-Lan Lieu

Queen Latifah & Paula Patton/A.J. Gibson

Queen Latifah and Paula Patton (The Perfect Match (2016)); news anchor A.J. Gibson

Connie Britton, Debbie Matenopoulos

Connie Britton and entertainment reporter Debbie Matenopoulos

Clark Gregg, Debbie Matenopoulos, Chi-Lan Lieu

Guest co-hostess Leeza Gibbons, Clark Gregg of Marvel's Agents of S.H.I.E.L.D., Entertainment Reporter Debbie Matenopoulos